Only the strong survives is set in the abandoned city of detroit, after a virus wipes out the human population. Canines are left the ruling species. The humans had been making a virus to use in the war, to wipe out the enemy. They had been testing when, in a freak accident, the virus bottle broke, escaping and spreading quickly. It killed the humans, yet had different effects on canines. It turned the canines rabbid, much like rabies, yet it didn't kill them. It turned them into aggressive, blood thirsty creatures who turned and attacked their friends and family. Some are immune to it. Now, it is every canine for themselves. It only takes a bite from an affected canine to be changed, so everyone's warry.
There is a new strand of virus going around the city. This strand of virus causes mutations within infected canines. Horns, extra tails, unnatural speed. Just more hardships for all the uninffected trying to survive. It only gets worse from there. The virus mutates one canine in a terrifying way. It gives the canine the ability to think, just like a canine that isn't infected. But it is still as bloodthirsty and aggressive as any other canine. A monster canine with the ability to plan. It means massive trouble for everybody in the city.